RU58841 Powder – 5g
| Application | Non-steroidal androgen receptor antagonist |
| Purity | >99% (third-party verified) |
| Amount | 5 grams |
| CAS | 154992-24-2 |
| Molar Mass | 369.33 g/mol |
| Chemical Formula | C17H18F3N3O3 |
| Synonyms | RU-58841, HMR-3690, PSK-3841 |
| Storage | Store at 2–8°C, away from light and moisture. Minimize open air exposure. |
| Terms | For laboratory research use only. Not for human or animal consumption. |
What Is RU58841 Powder?
RU58841 Powder is a research-grade non-steroidal androgen receptor antagonist at >99% purity, supplied in a 5g quantity for larger-scale research programs. RU58841 (HMR-3690, PSK-3841) was originally developed by Roussel Uclaf as a topically active antiandrogen for androgenetic alopecia (AGA). It acts as a competitive AR antagonist in scalp hair follicles, blocking DHT-mediated follicular miniaturization with a pharmacokinetic profile characterized by high local activity and rapid systemic metabolic inactivation.
The 5g raw powder format is ideal for researchers who need to prepare large-batch topical vehicle formulations, conduct longitudinal animal studies requiring consistent dosing, or perform analytical reference work such as HPLC validation and method development. RU58841 dissolves readily in ethanol, which is the standard vehicle for topical application research.
Research Applications
- Androgenetic alopecia (AGA): The gold-standard topical AR antagonist for preclinical hair loss research; validated in stump-tailed macaque and rodent models.
- Follicular AR pharmacology: Dermal papilla cell AR expression, DHT signaling, and follicular miniaturization studies.
- Vehicle optimization: Formulation research for scalp-penetrating ethanol or propylene glycol vehicles.
- Analytical reference: HPLC calibration, mass spectrometry method validation, quantitative bioanalysis development.
- Comparative antiandrogen studies: Benchmarking topical vs systemic AR antagonism alongside Andarine (S4) and Ostarine.
Related Products
Solution format: RU58841 | RU-58841 Solution (50mg/ml – 50ml). For broader androgen receptor research context, see RAD-140 (Testolone) — a full AR agonist at the opposite functional end of the spectrum from RU58841. For laboratory research use only.
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